Wednesday, July 18, 2018
 
 
Company News: Page (1) of 1 - 01/10/18 Email this story to a friend. email article Print this page (Article printing at MyDmn.com).print page facebook
Bisphosphonates Shown to Affect Dental Implant Surgery
 
(January 10, 2018)
Bisphosphonates Shown to Affect Dental Implant Surgery

Journal of Oral Implantology – Postmenopausal women often suffer from osteoporosis, resulting in a loss of bone mass and strength. To combat this disease, many women take bisphosphonates (BPs), a group of medicines that help slow or prevent bone loss. However, BP therapy in terms of successful dental implantation has not been well documented. Dental implantation tends to be highly predicative in terms of effectiveness, but when medication is introduced that will change the overall landscape of the mandible (jawbone) structure, implant failure can be a side effect.

Researchers from the Kanagawa Dental University Hospital and the Tokyo Medical and Dental University have recently performed a study focused on the use of BP therapy and its effect on the quality of the mandible. The researchers evaluated the bone mineral density and cortical bone thickness (the outer layer bone thickness) of the mandible, as well as how long-term BP therapy effected early implant failure.

This study included 25 female patients, at least 60 years of age, with a previous osteoporosis diagnosis, and who underwent dental implant surgery in the mandible between January 2010 and March 2013. The patients were divided into two groups: (1) the BP group consisted of 11 patients who had been taking BPs for more than one year, and (2) the remaining 14 patients were in the non-BP group and had been prescribed a type of hormone therapy. The patients were compared using several computed tomography (CT) scans of their mandible to gauge bone mineral densities, cortical bone thickness, and the effect that the duration of BP therapy had on these two factors.



The researchers found that in the BP group, 11 patients with a total of 25 implants had three (11.1%) of those implants fail in three (25%) different patients within one year. In the non-BP group, the 14 patients had a total of 28 implants. Every implant in the non-BP group survived. It was also found that the BP group had a higher bone mineral density than the non-BP group, and those patients with a longer duration of BP therapy had increased cortical bone thickness. Overall, the researchers believe that BP use is correlated with increased bone mineral density and cortical bone thickness.

The researchers conclude that, “These results indicate that BPs affect the quality and quantity of the cortical bone in the partially edentulous posterior mandible of patients with osteoporosis, which should be considered prior to treatment with dental implants in patients taking BPs."

This study was limited by both its small population size and the question of whether or not the medications used in the non-BP group had an effect on the mandible as well (which was not tested). However, the researchers have found that BP therapy does impact the mandible, and clinicians should be mindful that remodeling of the mandible could occur in patients receiving BP therapy, prior to beginning implant treatment.

Full text of the article, “Influence of Bisphosphonates on Implant Failure Rates and Characteristics of Postmenopausal Woman Mandibular Jawbone," Journal of Oral Implantology, Vol. 43, No. 5, 2017, is available at: http://joionline.org/doi/full/10.1563/aaid-joi-D-17-00015

###

About Journal of Oral Implantology
The Journal of Oral Implantology is the official publication of the American Academy of Implant Dentistry and of the American Academy of Implant Prosthodontics. It is dedicated to providing valuable information to general dentists, oral surgeons, prosthodontists, periodontists, scientists, clinicians, laboratory owners and technicians, manufacturers, and educators. The JOI distinguishes itself as the first and oldest journal in the world devoted exclusively to implant dentistry. For more information about the journal or society, please visit http://www.joionline.org

Read the full story at http://www.prweb.com/releases/2018/01/prweb15072875.htm.


Page: 1


Related Keywords:
Related Sites: DMN Newswire ,   HTN - Health Technology Net
Related Newsletter: Tutorial Finder ,   Review Seeker ,   DMN Newswire Newsletter
 
 
 
 
 
 
 
Seniors

Drugs
  • Healthcare IT Market 2018 - 2023 with SWOT Analysis regarding upcoming Changes and Technology Adaptations in Global Healthcare Sector
  • Implantable Medical Devices Market Predicted to be Worth US$ 49.8 Bn by 2024, Says TMR
  • Global Cosmetic Chemicals Industry
  • HMP's 8th Annual Amputation Prevention Symposium Expected to Draw 800 Clinicians to Chicago to Join the CLI Revolution
  • Progressive Care Inc. Announces Month-End Sales Figures Showing Increase in Year-Over-Year Prescriptions Filled in June 2018

    Cancer
  • Camurus Announces PDUFA Date for CAM2038 for the Treatment of Opioid use Disorder
  • Omega-3 Market to Reach US$ 16.37 Bn by 2023, Globally - QYResearch.com
  • Association of Community Cancer Centers and Advisory Board Launch 9th Annual Trends in Cancer Care Survey
  • Small Animal Imaging Market is Estimated to Grow at a Faster Pace With the Significant CAGR During the Forecast Period: Radiant Insights, Inc.
  • Presage Biosciences Closes Series D Financing with Takeda and Celgene, and Announces Appointment of Richard Klinghoffer, PhD as Chief Executive Officer
  •  
     
     
     
     
     





    Our Privacy Policy --- About The Health Technology - Contact Us - Advertise With Us - Privacy Guidelines