Bolt Biotherapeutics Appoints Nicole Onetto, M.D., to Board of Directors

REDWOOD CITY, Calif., Dec. 16, 2021 (GLOBE NEWSWIRE) — Bolt Biotherapeutics (Nasdaq: BOLT), a clinical-stage biotechnology company pioneering a new class of immuno-oncology agents that combine the targeting precision of antibodies with the power of both the innate and adaptive immune systems, today announced the appointment of Nicole Onetto, M.D., to its Board of Directors effective Dec. 14, 2021.

“Nicole’s extensive experience in clinical development and translational research makes her an excellent addition to the Bolt Biotherapeutics Board of Directors. Nicole’s work overseeing oncology drug development programs at cancer research institutions, biotechnology and pharmaceutical companies will be invaluable to Bolt as we advance our innovative immuno-oncology clinical programs and expand our pipeline,” said Randall Schatzman, Ph.D., CEO of Bolt Biotherapeutics.

“Developing safe and effective approaches to stimulating the innate and adaptive immune system is one of the next great frontiers for the treatment of patients with cancers at all stages of development,” said Dr. Onetto. “I look forward to sharing my experience and contributing to the groundbreaking work at Bolt Biotherapeutics in developing new immuno-oncology therapeutics that leverage the Boltbody™ ISAC platform.”

Dr. Onetto brings 30 years of experience primarily focused on the field of oncology at biotechnology, pharmaceutical and academic research institutions. She currently serves as an independent consultant in oncology, drug development and translational research, and on the Board of Directors at Viracta Therapeutics and Basilea Pharmaceutica. She previously served on the Board of Directors for NBE Therapeutics, Sierra Oncology, and ImmunoGen. Prior to that, Dr. Onetto held leadership roles at the Ontario Institute of Cancer Research, where she was Deputy Director and Chief Scientific Officer, and at ZymoGenetics (Bristol Myers Squibb) and OSI Pharmaceuticals (Astellas), where she held the position of Chief Medical Officer. Her career also includes senior management positions at Bristol Myers Squibb, Gilead Sciences, and Immunex Corporation (Amgen). Dr. Onetto earned her bachelor’s degree from the University of Paris, a master’s degree in Pharmacology from the University of Montréal, and her medical degree and a Hematology-Oncology Certificate from the University of Paris.

In connection with Dr. Onetto’s appointment, Ashish Khanna, Ph.D., will be stepping down from Bolt Biotherapeutics’ board of directors. Dr. Khanna has served as a member of the company’s board since July 2018.

Dr. Schatzman continued, “On behalf of the Board, I would like to express my deep appreciation for Ash’s contributions and strong support as we grew from a private research-stage to a public clinical-stage company.”

About Bolt Biotherapeutics, Inc.
Bolt Biotherapeutics, Inc. is a clinical-stage biotechnology company pioneering a new class of immuno-oncology agents that combine the targeting precision of antibodies with the power of both the innate and adaptive immune systems Bolt’s proprietary Boltbody™ Immune-stimulating Antibody Conjugate (ISAC) approach uses immunostimulants to engage and activate myeloid cells that directly kill tumor cells. This leads to the conversion of immunologically “cold” tumors to “hot” tumors. Bolt’s lead candidate, BDC-1001, is a Boltbody ISAC comprised of a HER2-targeting biosimilar of trastuzumab conjugated to one of Bolt’s proprietary TLR7/8 agonists for the treatment of patients with HER2-expressing solid tumors. Bolt is also advancing additional Boltbody ISAC product candidates targeting CEA and PD-L1. For more information, visit https://www.boltbio.com/.

Forward-Looking Statements
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Investor Relations and Media Contacts:
Karen L. Bergman
Vice President, Communications and Investor Relations
Bolt Biotherapeutics, Inc.
650-665-9295
kbergman@boltbio.com

Sarah McCabe
Stern Investor Relations, Inc.
212-362-1200
sarah.mccabe@sternir.com

Maggie Beller or David Schull
Russo Partners, LLC
646-942-5631
maggie.beller@russopartnersllc.com
david.schull@russopartnersllc.com