CAMBRIDGE, Mass., May 13, 2022 (GLOBE NEWSWIRE) — Pyxis Oncology, Inc. (Nasdaq: PYXS), a multi-asset multi-modality company focused on developing next-generation therapeutics for difficult to treat cancers, today reported financial results for its first quarter ended March 31, 2022. The Company ended the quarter with approximately $247 million in cash and cash equivalents.
Pyxis Oncology remains on target to file INDs for anti-EDB, PYX-201, and anti-Siglec-15, PYX-106, in the second half of 2022 and INDs for anti-CD123, PYX-203, and anti-KLRG1, PYX-102, in the second half of 2023. Further, as previously disclosed, the Company expects to provide an update on its anti-DLK1 ADC, PYX-202, in mid-2022.
Financial Update
About Pyxis Oncology, Inc.
Pyxis Oncology, Inc. is a multi-asset multi-modality company focused on defeating difficult to treat cancers and improving patient lives. By leveraging our fully integrated research, development and commercial capabilities, our expert team is efficiently building a diversified portfolio of next-generation therapeutics. Pyxis Oncology’s therapeutic candidates are designed to directly kill tumor cells, and to address the underlying pathologies created by cancer that enable its uncontrollable proliferation and immune evasion. Since its launch in 2019, Pyxis Oncology has developed a broad portfolio of novel antibody-drug conjugate product candidates, immuno-oncology, or IO, product candidates and monoclonal antibody, or mAb, preclinical discovery programs that it is developing as monotherapies and in combination with other therapies. To learn more about Pyxis Oncology, visit www.pyxisoncology.com.
Forward-Looking Statements
This press release contains forward-looking statements for the purposes of the safe harbor provisions under The Private Securities Litigation Reform Act of 1995 and other federal securities laws. These statements are often identified by the use of words such as “anticipate,” “believe,” “can,” “continue,” “could,” “estimate,” “expect,” “intend,” “likely,” “may,” “might,” “objective,” “ongoing,” “plan,” “potential,” “predict,” “project,” “should,” “to be,” “will,” “would,” or the negative or plural of these words, or similar expressions or variations, although not all forward-looking statements contain these words. We cannot assure you that the events and circumstances reflected in the forward-looking statements will be achieved or occur and actual results could differ materially from those expressed or implied by these forward-looking statements. Factors that could cause or contribute to such differences include, but are not limited to, those identified herein, and those discussed in the section titled “Risk Factors” set forth in Part II, Item 1A. of the Company’s Quarterly Report on Form 10-Q filed with SEC on May 13, 2022 and in our other filings with the SEC. These risks are not exhaustive. New risk factors emerge from time to time, and it is not possible for our management to predict all risk factors, nor can we assess the impact of all factors on our business or the extent to which any factor, or combination of factors, may cause actual results to differ materially from those contained in any forward-looking statements. In addition, statements that “we believe” and similar statements reflect our beliefs and opinions on the relevant subject. These statements are based upon information available to us as of the date hereof and while we believe such information forms a reasonable basis for such statements, such information may be limited or incomplete, and our statements should not be read to indicate that we have conducted an exhaustive inquiry into, or review of, all potentially available relevant information. These statements are inherently uncertain, and investors are cautioned not to unduly rely upon these statements. Except as required by law, we undertake no obligation to update any forward-looking statements to reflect events or circumstances after the date of such statements.
Investor and Media Contact
Courtney Dugan
VP, Head of Investor Relations and Corporate Communications
ir@pyxisoncology.com
—tables to follow—
PYXIS ONCOLOGY, INC. | ||||||||
Condensed Consolidated Statements of Operations and Comprehensive Loss (In thousands, except share and per share amounts) (Unaudited) |
||||||||
Three Months Ended March 31, | ||||||||
2022 | 2021 | |||||||
Operating expenses: | ||||||||
Research and development | $ | 20,071 | $ | 32,774 | ||||
General and administrative | 11,318 | 2,955 | ||||||
Total operating expenses | 31,389 | 35,729 | ||||||
Loss from operations | (31,389 | ) | (35,729 | ) | ||||
Other income (expense): | ||||||||
Interest income | 9 | 4 | ||||||
Change in fair value of derivative liability | — | (1,100 | ) | |||||
Total other income (expense) | 9 | (1,096 | ) | |||||
Net loss and comprehensive loss | $ | (31,380 | ) | $ | (36,825 | ) | ||
Net loss per common share – basic and diluted | $ | (0.97 | ) | $ | (27.26 | ) | ||
Weighted average shares of common stock outstanding – basic and diluted | 32,316,689 | 1,350,743 | ||||||
PYXIS ONCOLOGY, INC. | ||||||||
Condensed Consolidated Balance Sheets (In thousands, except share and per share amounts) (Unaudited) |
||||||||
March 31, 2022 | December 31, 2021 | |||||||
Assets | ||||||||
Current assets: | ||||||||
Cash and cash equivalents | $ | 247,087 | $ | 274,735 | ||||
Restricted cash | 1,472 | 1,472 | ||||||
Prepaid expenses and other current assets | 2,698 | 2,466 | ||||||
Total current assets | 251,257 | 278,673 | ||||||
Property and equipment, net | 995 | 1,007 | ||||||
Operating lease right-of-use assets | — | 232 | ||||||
Other assets, noncurrent | 449 | 109 | ||||||
Total assets | $ | 252,701 | $ | 280,021 | ||||
Liabilities and Stockholders’ Equity | ||||||||
Current liabilities: | ||||||||
Accounts payable | $ | 2,055 | $ | 11,951 | ||||
Accrued expenses and other current liabilities | 17,132 | 6,592 | ||||||
Operating lease liabilities, current portion | — | 165 | ||||||
Total current liabilities | 19,187 | 18,708 | ||||||
Total liabilities | 19,187 | 18,708 | ||||||
Commitments and contingencies | ||||||||
Stockholders’ equity: | ||||||||
Preferred stock | — | — | ||||||
Common stock | 32 | 32 | ||||||
Additional paid-in capital | 356,580 | 352,999 | ||||||
Accumulated deficit | (123,098 | ) | (91,718 | ) | ||||
Total stockholders’ equity | 233,514 | 261,313 | ||||||
Total liabilities and stockholders’ equity | $ | 252,701 | $ | 280,021 |
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