Clearmind Medicine Announces Successful Pre-Clinical Results in MEAI Treatment for Alcohol Consumption

Pre-clinical trial demonstrated high safety profile in addition to a significant suppressive effect on alcohol consumption

VANCOUVER, May 19, 2022 (GLOBE NEWSWIRE) — Clearmind Medicine Inc. (CSE: CMND, OTC Pink: CMNDF, FSE: CWY0) (“Clearmind” or the “Company”, a biotech company focused on discovery and development of novel psychedelic-derived therapeutics, today announced positive safety results of its proprietary molecule, MEAI, to treat alcohol abuse.

To evaluate the efficacy and safety of its psychedelic-derived treatment, Clearmind conducted preclinical trials, training groups of mice to consume alcohol for five weeks. The groups were then given varying daily doses of the new treatment, with intermittent access to alcohol and water. After two weeks, researchers found a significant reduction in alcohol consumption in mice receiving the treatment. The control group showed no statistical significant reduction.

Today’s safety results build on these positive efficacy findings and mark a significant milestone as Clearmind expects to conduct FDA-regulated clinical trials with humans later this year.

“We are tremendously pleased with the success of our preclinical trials to date, which have now demonstrated both safety and efficacy in reducing alcohol consumption,” said Dr. Adi Zuloff-Shani, Clearmind’s Chief Executive Officer “We believe that our novel, psychedelic-based treatment has the potential to help millions around the world suffering from alcohol abuse, along with a range of other mental health challenges. We look forward to our continued progress.”

Following the behavioral paradigm and to evaluate safety, histopathological testing was conducted on selected organs (heart, lungs, liver, kidneys, brain, pancreas, spleen, and thyroid gland) of tested animals to determine possible toxicological effects of MEAI. No treatment-related histological changes were observed amongst all MEAI treatment groups compared to control naive and vehicle animals in all the examined organs.

About Clearmind Medicine

Clearmind Medicine is a new biotech company focused on the discovery and development of novel psychedelic-derived therapeutics to solve widespread and underserved health problems, including alcohol use disorder, binge eating and depression.

The Israeli-Canadian company holds several patents for the non-hallucinogenic compound MEAI. The company intends to seek additional patents for its compounds whenever warranted and will remain opportunistic regarding the acquisition of additional intellectual property to build its portfolio.

Shares of Clearmind are listed for trading on the Canadian Securities Exchange under the symbol “CMND”, the Frankfurt Stock Exchange under the symbol “CWYO” and on the OTC pink under the symbol “CMNDF”.

For further information, please contact:
Investor Relations,
Email: invest@clearmindmedicine.com
Telephone: (604) 260-1566
General Inquiries,
Info@Clearmindmedicine.com
www.Clearmindmedicine.com

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