Mydecine Files Full Patent Application Covering MYCO-006 Family of Novel Short-Acting MDMA Analogs

Company aims to increase health equity by developing more accessible treatment modalities better suited for existing healthcare infrastructure

DENVER, July 19, 2022 (GLOBE NEWSWIRE) — Mydecine Innovations Group Inc. (NEO: MYCO) (OTC: MYCOF) (FSE: 0NFA) (“Mydecine” or the “Company”), a biotechnology company aiming to transform the treatment of mental health and addiction disorders, announced it has successfully synthesized multiple short-acting MDMA analogs. This family of analogs have been specifically designed by experts at Mydecine to have a shorter half life than traditional MDMA. The Company has named this family of novel molecules MYCO-006 and have applied for patent coverage with the World Intellectual Property Organization.

3,4-methylenedioxymethamphetamine (MDMA), commonly known as ecstasy, is a synthetic drug that acts as a stimulant and hallucinogen. In July 2021, Mydecine announced a provisional patent application for a family of MDMA-like compounds intended to reduce harm and improve safety compared to the traditional drug. Mydecine is targeting a 1-2 hour duration novel MDMA analog that will produce the same effects as traditional MDMA.

“There is a growing body of research that shows MDMA has the potential to make therapy more effective. From Rick Ingrasc’s early work in the early 70’s and 80’s with couples counseling, to MAPS more recent work with PTSD, MDMA has shown strong positive results removing interpersonal distrust and communication blocks without interfering with cognition. This effect allows therapy to be more effective. This is particularly important for patients suffering from conditions like post-traumatic stress disorder (PTSD), where patients focus on their traumas in order to identify, understand and change their thinking and behavior patterns,” said Chief Scientific Officer Rob Roscow.

Current recommended treatments for PTSD include trauma-focused psychotherapies, such as prolonged exposure, cognitive processing therapy, and eye movement desensitization and reprocessing. MDMA has been shown to increase feelings of well-being and interpersonal trust while decreasing feelings of fear and defensiveness. For these reasons, research has shown MDMA can increase the effectiveness of therapy.

Roscow goes on to say, “Although MDMA has shown great promise, the effects of the drug last 8 or more hours which is not ideal for a traditional medical setting. At Mydecine, we believe that in order to make treatments accessible to the majority of the population, we must make drug products that can be implemented into our existing healthcare infrastructure.”

Chief Medical Officer Dr. Rakesh Jetly said, “We applaud MAPS for their work with MDMA assisted therapy and the impressive efficacy data they have published. MAPS has shown their model works, but there may be times and conditions where a shorter acting medicine could be just as safe and effective while more efficient.”

“Psychedelic-assisted psychotherapy utilizing classic MDMA can take upwards of 12 hours to complete one session and a large amount of resources. By the time you’ve completed the pre-session preparation, the mystical experience, patient post-experience monitoring and post-therapy paperwork, both the patient and doctor are exhausted. Under this model, therapists would only be able to treat 2-4 patients per month. Our hope is by decreasing the half-life of MDMA, we can create treatments that can be easily repeated at your typical healthcare facility in order to make accessible and affordable treatments for patients,” added Dr. Jetly.

“For these treatment modalities to be adopted and accepted by the general medical community, there must be a drug product that can be administered at existing clinics and hospitals in less time, and that will be reimbursed by insurance providers. We believe shortening the half life of MDMA is an important necessary step to making this possible,” said CEO Josh Bartch. “Considering the incredible efficacy data being published on MDMA, and the frequent effect of boosting trust and well-being, we are incredibly excited about the potential to increase health equity for the large population in need with our MYCO-006 family of novel molecules.”

Mydecine’s mission is to become a trusted source of safe and effective medication-based treatments to address the unmet needs for mental health and addiction disorders.

Learn more about Mydecine’s drug development process by visiting their YouTube channel here.

About Mydecine Innovations Group
Mydecine Innovations GroupTM (NEO:MYCO) (OTC:MYCOF) (FSE:0NFA) is a biotechnology company developing innovative first- and-second-generation novel therapeutics for the treatment of mental health and addiction using world-class technology and drug development infrastructure. Mydecine was founded in 2020 to address a significant unmet need and lack of innovation in the mental health and therapeutic treatment environments. Our global team is dedicated to efficiently developing new therapeutics to treat PTSD, depression, anxiety, addiction and other mental health disorders. The Mydecine business model combines clinical trials and data outcome, technology, and scientific and regulatory expertise with a focus on psychedelic therapy, as well as other novel, non-psychedelic molecules with therapeutic potential. By collaborating with some of the world’s foremost authorities, Mydecine aims to responsibly fast-track the development of new medicines to provide patients suffering from mental health disorders with safe and more effective treatment options. Mydecine Innovations Group is headquartered in Denver, Colorado, USA, with international offices in Leiden, Netherlands.

For more information, please contact:
Media Contact
Morgan Kervitsky, Director of Administration
pr@mydecineinc.com

Investor Relations
Morgan Kervitsky, Director of Administration
contact@mydecineinc.com

On behalf of the Board of Directors:
Joshua Bartch, Chairperson and CEO
contact@mydecineinc.com

For further information about Mydecine Innovations Group, Inc., please visit the Company’s profile on SEDAR at www.sedar.com or visit the Company’s website at www.mydecine.com.

This news release contains forward-looking information within the meaning of Canadian securities laws regarding the Company and its business, which relate to future events or future performance and reflect management’s current expectations and assumptions. Often but not always, forward-looking information can be identified by the use of words such as “expect”, “intends”, “anticipated”, “believes” or variations (including negative variations) of such words and phrases, or state that certain actions, events or results “may”, “could”, “would” or “will” be taken, occur or be achieved. Such forward-looking statements reflect management’s current beliefs and are based on assumptions made by and information currently available to the Company. Readers are cautioned that these forward-looking statements are neither promises nor guarantees, and are subject to risks and uncertainties that may cause future results to differ materially from those expected including, without limitation, risks regarding the COVID-19 pandemic, the availability and continuity of financing, the ability of the Company to adequately protect and enforce its intellectual property, the Company’s ability to bring its products to commercial production, continued growth of the global adaptive pathway medicine, natural health products and digital health industries, and the risks presented by the highly regulated and competitive market concerning the development, production, sale and use of the Company’s products. Although the Company has attempted to identify important factors that could cause actual results to differ materially from those contained in forward-looking information, there may be other factors that cause results not to be as anticipated, estimated or intended. There can be no assurance that such information will prove to be accurate, as actual results and future events could differ materially from those anticipated in such information. These forward-looking statements are made as of the date hereof and the Company does not assume any obligation to update or revise them to reflect new events or circumstances save as required under applicable securities legislation.