Allschwil, Switzerland, January 5, 2024
Basilea Pharmaceutica Ltd, Allschwil (SIX: BSLN), a commercial-stage biopharmaceutical company committed to meeting the needs of patients with severe bacterial and fungal infections, reported today on the progress within its R&D portfolio in 2023 and upcoming milestones and timelines.
David Veitch, Chief Executive Officer, said: “We have achieved significant milestones in 2023 and remain committed to executing our strategy to drive long-term value creation. With the addition of three new assets to our clinical development pipeline, led by the very promising antifungal fosmanogepix, we are delivering on our goal of creating a balanced portfolio of innovative drug candidates for the treatment of severe bacterial and fungal infections. Furthermore, we have established ourselves as the partner of choice for companies seeking support in the development of their assets, with a focus on differentiation and commercial positioning. The continued commercial success of Cresemba and, pending US approval, the increasing revenue contributions from Zevtera, provide us with the financial strength to both advance our new programs and continue to expand our exciting R&D portfolio, supporting us in achieving our strategic goal of becoming a leading anti-infectives company.”
Maintaining its strong momentum, the commercial performance of Cresemba triggered a number of milestone payments to Basilea. By year-end 2023, Cresemba was marketed in more than 70 countries, including the United States (US), most EU member states, China and Japan. According to the latest available market data, total global in-market sales of Cresemba in the twelve-month period between October 2022 and September 2023 amounted to USD 445 million, a 22 percent growth year-on-year.1
Portfolio key highlights 2023
Cresemba® (isavuconazole) commercial lifespan extension
Zevtera® (ceftobiprole) US NDA under review
Basilea expects to enter into a commercialization partnership agreement for ceftobiprole in the US prior to the FDA decision.
Pipeline broadened with promising new clinical drug candidates
For fosmanogepix, Basilea anticipates to start a phase 3 study in invasive yeast infections mid-2024 and a phase 3 study in invasive mold infections, by year-end 2024. For BAL2062 and tonabacase, the focus for 2024 will be on preclinical profiling in order to define the optimal positioning and clinical development plans for these assets. Following a re-prioritization of its earlier stage research pipeline and re-allocation of resources, Basilea decided at year-end 2023 to discontinue the preclinical program on inhibitors of DXR, an enzyme in the bacterial isoprenoid biosynthesis pathway.5
Throughout 2024, we aim to continue expanding our R&D portfolio, through the identification of innovative, commercially attractive assets, addressing unmet medical needs in the treatment of severe fungal and bacterial diseases.
About Basilea
Basilea is a commercial-stage biopharmaceutical company founded in 2000 and headquartered in Switzerland. We are committed to discovering, developing and commercializing innovative drugs to meet the needs of patients with severe bacterial and fungal infections. We have successfully launched two hospital brands, Cresemba for the treatment of invasive fungal infections and Zevtera for the treatment of bacterial infections. In addition, we have preclinical and clinical anti-infective assets in our portfolio. Basilea is listed on the SIX Swiss Exchange (SIX: BSLN). Please visit basilea.com.
Disclaimer
This communication expressly or implicitly contains certain forward-looking statements, such as “believe”, “assume”, “expect”, “forecast”, “project”, “may”, “could”, “might”, “will” or similar expressions concerning Basilea Pharmaceutica Ltd, Allschwil and its business, including with respect to the progress, timing and completion of research, development and clinical studies for product candidates. Such statements involve certain known and unknown risks, uncertainties and other factors, which could cause the actual results, financial condition, performance or achievements of Basilea Pharmaceutica Ltd, Allschwil, to be materially different from any future results, performance or achievements expressed or implied by such forward-looking statements. Basilea Pharmaceutica Ltd, Allschwil is providing this communication as of this date and does not undertake to update any forward-looking statements contained herein as a result of new information, future events or otherwise.
For further information, please contact:
Peer Nils Schröder, PhD
Head of Corporate Communications & Investor Relations |
|
Phone | +41 61 606 1102 |
media_relations@basilea.com investor_relations@basilea.com |
This press release can be downloaded from www.basilea.com.
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