Codoxo Achieves NIST 800-53 Revision 5 Compliance for Second Consecutive Year

Healthcare AI company maintains regulatory standards for highest security and privacy compliance, supporting strategic growth readiness

DULUTH, Ga., July 15, 2025 /PRNewswire/ — Codoxo, the trusted provider of AI-driven healthcare cost containment and payment integrity solutions, today announced it has achieved NIST 800-53 Revision 5 compliance for the second consecutive year––reinforcing Codoxo’s sustained commitment to the highest standards of data security, privacy, and operational excellence.

Developed by the National Institute of Standards and Technology, NIST 800-53 is a gold-standard cybersecurity framework used to manage risk across federal and critical infrastructure systems. Codoxo’s adherence to this framework ensures its platform meets the rigorous requirements of both federal agencies and commercial healthcare organizations, affirming its role as a secure, reliable partner in the protection of sensitive health information.

“Security is not a single milestone, but an ongoing responsibility,” said Dr. Musheer Ahmed, CEO and Founder of Codoxo. “By securing and sustaining NIST 800-53 Rev. 5 compliance, Codoxo’s technology and services adhere to the highest industry standard for security, maintaining a trustworthiness standard that healthcare payers and government agencies demand. As we approach our next phase of growth, we are proud to lead with AI and generative AI that makes compliance and security foundational.”

Maturity and Continuity in Security Practices

Securing this achievement for a second year validates that Codoxo’s security controls are not only compliant, but operationally embedded and repeatable across its entire cost-containment platform. Highlights include:

• Healthcare Data Protection: Renewal of NIST compliance underscores Codoxo’s continued dedication to safeguarding protected health information (PHI) and maintaining trust with health plans, government entities, and healthcare providers nationwide.
• Enterprise and Government-Grade Readiness: Codoxo’s platform meets the security demands of federal and commercial healthcare organizations through robust controls for encryption, access management, system monitoring, and incident response—all mapped to the NIST 800-53 framework. This compliance reflects Codoxo’s commitment to adaptable, enterprise-grade security that aligns with both federal standards like FedRAMP and industry regulations such as HIPAA.
• Security by Design: Codoxo’s platform leverages single-tenant AWS architecture with customer-specific encryption keys, automated compliance monitoring, and strict data isolation ensuring that security is built into every layer of its AI model lifecycle.

“Maintaining NIST compliance year-over-year isn’t just a routine exercise for Codoxo, it reflects a strategic investment,” said Prasoon Saurabh, Vice President of Engineering. “From platform architecture to every layer of our AI lifecycle, Codoxo builds the most secure, scalable, and trusted systems by design.”

Codoxo also holds the HITRUST Risk-based, 2-year (r2) Certification, which it has re-certified over multiple cycles—further reinforcing its leadership in healthcare data protection.

About Codoxo
With a mission to make healthcare more affordable and effective for everyone, Codoxo is the leading provider of generative AI and advanced artificial intelligence-driven solutions that empower healthcare payers to proactively identify and resolve payment integrity issues at the earliest stages of the claim lifecycle—ranging from pre-claim to prepay and postpay. The Codoxo Unified Cost Containment Platform leverages generative AI to help payers drive savings through provider education, data mining, medical record reviews, fraud detection, medical policy and provider contract compliance, concept ideation, and audit and case management. Our software-as-a-service applications are built on our proven Forensic AI Engine, which uses patented AI-based technology to identify payment issues far faster and earlier than traditional techniques. Codoxo is a Fierce Healthcare Innovation Award winner and has been recognized by the Inc. 5000 list for growth. Our solutions are HIPAA-compliant and operate in a HITRUST-certified environment. For additional information, visit www.codoxo.com.

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SOURCE Codoxo