Radicle Science Launches Radicle Discovery Gen 2, its Next-Generation Clinical Research Offering

Health tech pioneer unveils a powerful, vertically integrated platform for an intelligent, customizable, and insights-rich experience that outpaces outdated CRO models.

SAN DIEGO, July 22, 2025 /PRNewswire/ — Radicle Science, a health tech trailblazer on a mission to bring clinical evidence to natural products and wellness, launches Radicle Discovery Gen 2, the next version of its pioneering Proof-as-a-Service platform. Combining rigorous clinical trials, AI, data, and crowdsourcing to validate the effects of natural products across diverse populations, Radicle Discovery Gen 2 is a fundamental upgrade to what brands can expect from a clinical trial.

“Radicle Discovery Gen 2 isn’t just an upgrade—it’s a complete reimagination of clinical research, starting with the end in mind,” said Dr. Jeff Chen and Pelin Thorogood, co-founders of Radicle Science. “We’ve engineered an intelligent platform that combines cutting-edge AI, validated biomarkers, and exponentially flexible trial designs to deliver the kind of speed, precision, and depth the wellness industry has never seen. This is more than innovation, it’s a revolution in how natural products are clinically validated and precision targeted to subpopulations. Our clients demanded more. Gen 2 delivers exponentially more—without the exponential cost.”

A Category-Redefining Platform

Radicle Discovery Gen 2 is a next-generation clinical trial engine for natural products, built from the ground up to go beyond the limitations of traditional CROs. The result is a tech-enabled, deeply customizable service that accelerates speed-to-claim, increases the likelihood of success, and unlocks richer insights—standard, not as an “add on.”

• Expanded Health Indications & Customization:
  Gen 2 supports research across dozens of top health categories, enabling advanced customization options, including outcomes, eligibility, duration, and statistical plan.
• Flexible Trial Designs:
  Radicle’s adaptive design approach provides trial flexibility for a variety of scientific or marketing goals. Gold-standard, double-blind, randomized, placebo-controlled clinical trials support the development of strong claims. Open-label trials allow brands to test variations on packages, usage instructions, flavors, or product forms. And brands can leverage In-home use tests (IHUTs) to conduct consumer sensory or impression research.
• Expanded Physical Biomarkers:
  Now offering nearly 100 blood, saliva, stool, and vaginal biomarkers with clinically validated direct-to-consumer (DTC) testing kits.
• Expanded Digital Biomarkers and Wearables:
  Smart tech tools capture a vast amount of rich and real-time health data that has been largely unavailable in traditional clinical research. Radicle’s menu of digital measurements includes Bluetooth-connected scales, smart-phone based cognition tests, AI-analyzed facial scans, and integrations with wearables including Apple Watch, Oura Ring, and FitBit.
• Precision Insights:
  Radicle’s proprietary Precision Insights analytics are included in every Gen 2 trial at no additional cost. Made possible by large diverse trial data combined with advanced biostatistics and AI cluster analysis, Precision Insights arms scientific and commercial teams with actionable intelligence on how the product’s benefits, usage behavior, consumer perceptions, and side effects differ amongst subpopulations. These never-before-seen insights drive evidence-based personalization and targeting to boost ROI–fueling both precision health strategies and marketing campaigns.

Additionally, Radicle is now streamlining the management of its large-scale trials—often involving thousands of participants—by augmenting its research team with AI agents. These intelligent agents assist with participant communication and engagement to enhance responsiveness, scalability, and consistency. By handling time-intensive coordination tasks, the AI agents free up Radicle’s human scientists to focus on higher-order activity, improving the overall trial experience without sacrificing the human touch. We also use AI to learn from our aggregate anonymized clinical dataset built through collaborations across the industry. This is the largest pool of clinical evidence ever generated on wellness products, and helps make Radicle trials more successful for our clients and participants.

Radicle Discovery Gen 2 replaces outdated, rigid contract research models with a more modern, customizable, and insights-rich experience. Built for speed-to-claim, speed-to-market, and speed-to-insight, Radicle Science continues to transform what a clinical trial can be and what it can deliver to unlock the future of wellness.

About Radicle Science
Radicle Science is a health tech trailblazer on a mission to bring clinical evidence to natural products and wellness. Its pioneering proof-as-a-service platform combines AI, clinical trials, data, and crowdsourcing to rigorously validate the effects of natural products across diverse populations—at unprecedented scale and speed. It delivers improved health outcomes for consumers, innovative R&D insights for brands, and bridges the long-standing gap between consumer belief and scientific validation. Radicle Science has received numerous accolades, including Fast Company’s “World Changing Idea” and Nutritional Outlook’s Best of Industry “Service Provider.” Since its launch in 2021, Radicle Science has conducted placebo-controlled trials on wellness products in over 71,000 Americans—more than the total enrolled in all FDA drug approval trials during the same period. By including populations historically underrepresented in research, the company is advancing health equity and setting a new standard for evidence-based, personalized care. www.radiclescience.com

Media Contact:
Heather Granato
Strategic Marketing Advisor
(480) 390-4327
heather.granato@radiclescience.com

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SOURCE Radicle Science